Women who are having difficulty conceiving may want to cut back on their soy consumption after a mouse study reveals that dietary exposure to genistein, a compound found in soy foods, can reduce the odds of a successful pregnancy in multiple ways.The study examined the impact of genistein exposure on oocytes, or eggs, from adult mice and found it can impair oocyte maturation, reduce their potential to become fertilized and hamper the growth of the newly formed embryo. The results reveal how natural compounds like genistein may have both risks – it can act as an endocrine disurptor to affect female reproduction – and benefits - such as protecting the heart.
Resources
Jefferson, W, R Newbold, E Padilla-Banks and M Pepling. 2006. Neonatal genistein treatment alters ovarian differentiation in the mouse: inhibition of oocyte nest breakdown and increased oocyte survival. Biology of Reproduction 74(1): 161-168.
Jefferson, W, R Newbold, E Padilla-Banks and M Pepling. 2006. Neonatal genistein treatment alters ovarian differentiation in the mouse: inhibition of oocyte nest breakdown and increased oocyte survival. Biology of Reproduction 74(1): 161-168.
Jefferson, WN, E Padilla-Banks and RR Newbold. 2005. Adverse effects on female development and reproduction in CD-1 mice following neonatal exposure to the phytoestrogen genistein at environmentally relevant doses. Biology of Reproduction 73(4): 798-806.
Kuhnle, GG, C Dell'Aquila, SM Aspinall, SA Runswick, AA Mulligan and SA Bingham. 2008. Phytoestrogen content of beverages, nuts, seeds, and oils. Journal of Agricultural and Food Chemistry 56: 7311-7315.
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Stories of Pregnancy over 44 years old - sharing stories I find online, for inspiration!
Pregnancy Stories by Age - Daily blog of hope & inspiration!
Stories of Pregnancy over 44 years old - sharing stories I find online, for inspiration!
