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Friday, July 24, 2009

Mutation causing one type of male infertility found

Friday, July 24, 2009
Mutation causing one type of male infertility foundResearchers have found a genetic mutation that lies behind one type of male infertility and may have been a cause of unsuccessful In-Vitro Fertilization (IVF) treatments in some couples.

The mutation lies in one specific protein present in sperm called PLC zeta. Recent research, in which the Oxford team also played a significant role, has shown that sperm transfers PLC zeta to the egg on fertilisation. The protein initiates a process called 'egg activation' which sets off all the biological processes necessary for development of the embryo.



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